Effects of sunlight on the eye
10.3980/j.issn.1672-5123.2020.2.01
- VernacularTitle:自然光照对眼部的影响
- Author:
Zhen-Zhen Liu
1
,
2
,
3
Author Information
1. 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510000, Guangdong Province, China
2. 2Guangdong Engineering Technology Research and Development Center of Eye-protection Lamp, Guangdong Guangyang Electric Appliance Co., Ltd., Zhongshan 528415, Guangdong Province, China
3. Co-first authors:Zhen-Zhen Liu, Shao-Fan Chen, and Tong-Yong Yu.
- Publication Type:Journal Article
- Keywords:
sunlight;
ultraviolet light;
ocular structure;
oxidative stress;
DNA damage
- From:
International Eye Science
2020;20(2):191-196
- CountryChina
- Language:Chinese
-
Abstract:
Sunlight consists of lights of continuous spectra. Ultraviolet light and blue light in the sunlight have higher energy. High dose exposure to sunlight can cause direct cellular damage. In the eye, sunlight is known to cause pathological changes in various eye structures. We reviewed the studies on the role of sunlight in corneal diseases, cataracts, glaucoma, and age-related macular degeneration in recent years. Possible sunlight-triggered signaling pathways and mechanisms in the eye are summarized. Excessive exposure to sunlight may lead to increased DNA damage, aberrant protein modification and aggregation, and oxidative stress of ocular tissues, and thus results in the development of ocular diseases. Accordingly, physical protection, topical and/or oral antioxidants and small molecules blocking sunlight-activated signal pathways could be used independently or combinedly to prevent and reduce sunlight-induced ocular damages.
- Full text:202002001.pdf
