Formation mechanism of neutrophil extracellular traps and their role in liver diseases
10.3969/j.issn.1001-5256.2020.01.049
- VernacularTitle:中性粒细胞胞外诱捕网的形成机制及在肝病中的作用
- Author:
Lin CAO
1
;
Qian LI
;
Longshan JI
Author Information
1. Shanghai Key Laboratory of Traditional Chinese Clinical Medicine & Laboratory of Cellular Immunology, Shanghai 200120, China）
- Publication Type:Research Article
- Keywords:
extracellular traps；hepatitis B, chronic；liver cirrhosis；liver neoplasms
- From:
Journal of Clinical Hepatology
2020;36(1):205-207
- CountryChina
- Language:Chinese
-
Abstract:
Neutrophil extracellular traps (NETs) have recently been found to be a new immune mechanism for neutrophils to kill pathogens. The main component of NETs is DNA, with granular proteins of different sizes attached to the surface. NETs play different roles in various liver diseases such as hepatic ischemia-reperfusion injury, chronic hepatitis B, liver cirrhosis, and liver cancer. This article reviews the formation mechanism, structure, and role of NETs in liver diseases.
