Biochemical response and integrated traditional Chinese and Western medicine therapy for primary biliary cholangitis
10.3969/j.issn.1001-5256.2020.01.004
- VernacularTitle:原发性胆汁性胆管炎的熊去氧胆酸生化应答预测及中西医结合治疗
- Author:
Xiaojing WANG
1
;
Yao LIU
;
Xianbo WANG
Author Information
1. Department of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
- Publication Type:Research Article
- Keywords:
primary biliary cholangitis;
biochemical response;
TCM WM therapy
- From:
Journal of Clinical Hepatology
2020;36(1):26-30
- CountryChina
- Language:Chinese
-
Abstract:
Primary biliary cholangitis (PBC) is an immune-mediated chronic and progressive intrahepatic cholestasis disease. Treatment with ursodeoxycholic acid (UDCA) can significantly improve the prognosis of patients with PBC, but some patients still have poor response to UDCA, which is the main risk factor for disease progression. Several evaluation models and scoring systems based on biochemical response have been applied to screen out patients with poor response in clinical practice. Integrated traditional Chinese and Western medicine therapy for PBC has certain advantages in improving the symptoms, liver biochemistry, fibrosis indices, and biochemical response rate of PBC patients and thus holds promise for clinical application; however, further improvement is needed for experimental design and efficacy evaluation.
