Epidemiology of nosocomial infection in recipients after renal transplantation: a single-center analysis
10.3969/j.issn.1674-7445.2019.04.013
- VernacularTitle:肾移植受者术后医院感染流行病学单中心分析
- Author:
Yibin TAN
1
;
Xuelan JIN
;
Yuan LI
;
Songjie WU
;
Ying WANG
;
Jia TIAN
;
Shihui SONG
;
Yanfeng WANG
Author Information
1. Nosocomial Infection Management Office, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
- Publication Type:Research Article
- Keywords:
Renal transplantation;
Fungus;
Bacterium;
Nosocomial infection;
Pathogen;
Epidemiological study
- From:
Organ Transplantation
2019;10(4):429-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epidemiological characteristics of renal transplantation recipients, effective prevention and control measures. Methods A total of 456 renal transplant recipients were monitored from January 2014 to December 2017. Postoperative infection including baseline data, infection site and infectious pathogen type was analyzed. Results Among 456 renal transplant recipients, 78 cases (17.1%) developed nosocomial infection. Postoperative infection time was 9(3-21) d. Infection sites mainly included the lower respiratory tract, urinary system and blood infection. Infection pathogens consisted of Staphylococci (n=13), Enterococcus faecium (n=6), fungi (n=6), Stenotrophomonas maltophilia (n=4), Acinetobacter baumannii (n=4), Pseudomonas aeruginosa (n=4), Staphylococcus epidermidis (n=4), Klebsiella pneumoniae (n=1), Escherichia coli (n=1) and other negative bacteria (n=9). Among them, 11 cases (14%) were infected with multi-drug resistant bacteria, and 4 cases died. Conclusions In renal transplant recipients, the incidence of nosocomial infection is relatively high, with early postoperative onset, common multiple drug-resistant bacterial infection and high mortality. Preoperative preparations should be fully implemented, postoperative lower respiratory tract infection should be actively prevented and prevention and treatment measures for multidrug-resistant bacteria should be standardized.
