Analysis of infection status in severe pneumonia cases infection with influenza A virus in Nanchang from 2013 to 2018
10.16462/j.cnki.zhjbkz.2019.02.022
- Author:
Feng-lan HE
1
;
Wen XIA
;
Xian-sheng NI
;
Wen-tang SONG
;
Guo-yin FAN
;
Jun-ling TU
;
Jing-wen WU
Author Information
1. Microbiology Laboratory Nanchang Center for Disease Control and Prevention, Nanchang 330038, China
- Publication Type:Research Article
- Keywords:
Severe pneumonia;
Influenza A virus;
Etiology;
Epidemiology
- From:
Chinese Journal of Disease Control & Prevention
2019;23(2):233-236
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the distribution and disease characteristics of influenza virus A in severe pneumonia cases in Nanchang city, so as to provide evidence for clinical prevention and treatment of severe pneumonia cases. Methods The respiratory samples and clinical case data of severe pneumonia cases were collected and the etiology and epidemiology were analyzed in Nanchang from April 2013 to March 2018. Results From April 2013 to March 2018, 261 case patients of severe pneumonia from 17 medical institutions in Nanchang were enrolled. 77 cases was detected as positive for influenza A virus nucleic acid, accounting for 29.50% of the total cases, as follow: 39 cases of A (H1N1pdm) influenza, 13 A (H3), 16 H7N9 and 3 H10N8 avian influenza. Cases were mainly concentrated in winter and spring (from December to May of next year, with median age 48 of years, including 48 males and 31 females. 21 cases of human infection with H7N9/H10N8 avian influenza were reported in Nanchang during 5 years, with the fatality rate of 33.33%. 90.48% (19/21) cases were detected by unexplained pneumonia surveillance system. The median age was 69 years, most of them had underlying diseases and a clear history of poultry contact. Conclusions Nearly 30% of the severe pneumonia cases in Nanchang city were infected with influenza A virus, among which influenza A (H1N1pdm) virus was the main epidemic strain. All deaths were caused by avian influenza virus infection.
