Advances in immunotherapy of Alzheimer's disease with traditional Chinese medicine
10.16438/j.0513-4870.2017-1013
- VernacularTitle:中药免疫治疗阿尔茨海默病的研究进展
- Author:
Sha-sha WANG
1
;
Zhao ZHANG
2
;
Xin ZHANG
1
;
Qian LONG
1
;
Wen-bin HE
1
;
Nai-hong CHEN
1
Author Information
1. Shanxi University of Traditional Chinese Medicine, Taiyuan 030619, China
2. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
- Publication Type:SPECIAL REPORTS
- Keywords:
Alzheimer's disease;
immunotherapy;
inflammation;
traditional Chinese medicine
- From:
Acta Pharmaceutica Sinica
2018;53(7):1023-1029
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease (AD) is a type of common neurodegenerative disease. The main clinical symptom of the disease is progressive cognitive dysfunction, which has no effective therapy yet. With the in-depth immunology study in the central nervous system, studies in different fields such as preclinical phase, genetics and bioinformatics have shown that immune dysfunction contribute to the pathogenesis of AD, including the beginning, maintenance and deterioration stage in AD. China has a wealth of natural medicine resources and clinical experiences. A large number of natural drugs and effective components both can regulate the immune function and ameliorate the symptoms in AD. This review summarizes the researches of ameliorating the symptoms in AD through immunization regulation in recent years with an aim to provide new ideas and clues in the study of new anti-AD drugs using natural medicines.
