Regulation of integrin gene expression
10.16438/j.0513-4870.2017-0515
- VernacularTitle:整合素的基因表达调控
- Author:
Yi-xuan ZHANG
1
;
Rong-guang SHAO
1
;
Hong-wei HE
1
Author Information
1. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
- Publication Type:REVIEWS
- Keywords:
integrin;
transcriptional regulation;
transcription factor;
miRNA
- From:
Acta Pharmaceutica Sinica
2017;52(11):1647-1651
- CountryChina
- Language:Chinese
-
Abstract:
Integrin is a class of important cell surface molecules involved in cell proliferation, differentiation, adhesion and migration processes, which play an important role in a variety of pathological processes. In recent years, with the research in integrin regulation and the treatment of tumor, tissue fibrosis, and other fields, integrin has gradually become a new target in the diagnosis and treatment of diseases. In this article, we provide a summary on the advances of the regulation of integrin gene expression.