A new triterpenic acid from the roots of Rosa laevigata
- VernacularTitle:金樱子根中一个新三萜酸
- Author:
Yu-lu LI
1
;
Hua-nian DAI
1
;
Guo-xu MA
2
;
Wen ZHANG
2
;
Tong-yu WU
2
;
Yun-qing WANG
1
;
Jie-ming ZOU
3
;
Xiao-qing ZHONG
3
;
Yan-lin ZHOU
3
;
Jing-quan YUAN
1
;
Xu-dong XU
2
;
Wei YI
4
Author Information
- Publication Type:ORIGINAL ARTICLES
- Keywords: Rosa laevigata; chemical compositions; triterpenic acid; 19α-OH-3β-E-feruloyl corosolic acid
- From: Acta Pharmaceutica Sinica 2017;52(3):425-429
- CountryChina
- Language:Chinese
- Abstract: This study was designed to investigate triterpenoids from the roots of Rosa laevigata Michx. The silica gel column chromatography was used to separate the chemical constituents from the roots of Rosa laevigata Michx. HPLC was used to analyze its purity and chemical constitution. Spectroscopy methods were used to determine their structures. Five constituents were isolated and identified as19α-OH-3β-E-feruloyl corosolic acid (1), 23-hydroxy-tormentic acid (2), 2α, 3β, 19α, 23-tetrahydroxy-12-en-28-oleanolic acid (3), 2α, 3α, 20β-trihydroxyurs-13 (18)-en-28-oic-acid (4), 2α, 3β, 20β-trihydroxyurs-13 (18)-en-28-oic-acid (5). Compound 1 was assigned as a new compound, compounds 4, 5 were obtained from the genus Rosa for the first time.
