Current status of ion channels as drug targets for diabetic neuropathic pain
10.16438/j.0513-4870.2016-0928
- VernacularTitle:离子通道作为糖尿病神经性疼痛药物靶点的现状研究
- Author:
Yu ZHOU
1
;
Xiao-liang WANG
1
;
Hai-bo YU
1
Author Information
1. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
- Publication Type:REVIEWS
- Keywords:
diabetic neuropathic pain;
ion channel;
potassium channel;
sodium channel;
calcium channel
- From:
Acta Pharmaceutica Sinica
2017;52(3):355-361
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic neuropathic pain (DNP) is the most common chronic complication of diabetes mellitus, significantly affecting people's quality of life. Studies have indicated that ion channels play a very important role in the occurrence of DNP. This review provides a summary in the role of ion channels in diabetic neuropathic pain and treatment strategies for diabetic neuropathy targeting ion channels.
