Dose-response relationship between light at night and nonalcoholic fatty liver in steel workers
10.16462/j.cnki.zhjbkz.2019.11.011
- Author:
Zhen-de WANG
1
;
Han WANG
;
Li YANG
;
Chao XUE
;
Yong-bin WANG
;
Sheng-kui ZHANG
;
Ju-xiang YUAN
Author Information
1. Department of Epidemiology and Health Statistics, School of Public Health, North China University of Technology, Tangshan 063000, China
- Publication Type:Research Article
- Keywords:
Light at night;
Nonalcoholic fatty liver;
Steel workers;
Restricted cubic spline
- From:
Chinese Journal of Disease Control & Prevention
2019;23(11):1353-1357,1363
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between light at night (LAN) and nonalcoholic fatty liver (NAFLD) in steel workers. Methods Relevant information was collected through questionnaires, physical examinations and blood biochemical analysis. Using restricted cubic spline (RCS) and mutiple Logistic regression model to explore the relationship between LAN and NAFLD based on a cross-sectional study. Results The prevalence of NAFLD was 33.8% (2 594 / 7 664) in steel workers. After adjusting for age, sex, marriage, educational level, smoking, drinking, body mass index, luminous intensity in life, liver enzyme metabolism, blood lipid level, physical activity, diet, sleep duration, shift work, high temperature, noise, dust, and carbon monoxide exposure, the RCS model showed a nonlinear dose-response relationship between LAN and NAFLD ( 2=71.59, P<0.001 for overall association test and 2=16.92, P<0.001 for nonlinear test); Multivariate Logistic regression model showed that after adjusting for all confounding factors, when the LAN in the 1 178 d ~ 2 017 d and 2 017 d ~ group, the prevalence of NAFLD increased by 21.7% (OR=1.217, 95% CI: 1.027-1.441) and 47.9% (OR=1.479, 95% CI: 1.240-1.763), respectively, when compared with the group LAN<1 178 d. Conclusion There is a nonlinear dose-response relationship between LAN and NAFLD in steel works.
