Carriage prevalence and drug resistance profile of MRSA and MSSA strains isolated from newborns
10.16462/j.cnki.zhjbkz.2019.10.027
- Author:
Ying-ying WANG
1
;
Xin ZHOU
;
Chuan-an WU
;
Hui-jie ZHENG
;
Hao-qu ZHENG
;
Zhen-jiang YAO
Author Information
1. Faculty of Epidemiology and Health Statistics,School of public health, Guangdong pharmaceutical university, Guangzhou 510310, China
- Publication Type:Research Article
- Keywords:
Newborns;
MRSA;
MSSA;
Carriage prevalence;
Antibiotics resistance profile
- From:
Chinese Journal of Disease Control & Prevention
2019;23(10):1297-1300
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the carriage prevalence and antibiotics resistance profile of methicillin-resistant staphylococcus aureus(MRSA) and methicillin-sensitive staphylococcus aureus(MSSA) strains isolated from newborns. Methods A cross-sectional study was conducted in two hospitals in Shenzhen from August to November 2015. Cotton swab samples were collected from 1834 newborns. Staphylococcus aureus was identified by general laboratory tests, and antimicrobial-susceptibility profiles was tested. Results In total, 3.27% (60/1 834) Staphylococcus aureus (SA) strains were isolated, including 0.82% (15/1 834) MRSA and 2.45% (45/1 834) MSSA. Most MRSA and MSSA strains were resistant to penicillin and erythromycin but less than 10% strains resistant to linezolid. Drugs resistance rates of MRSA to erythromycin, moxifloxacin and clindamycin were all higher than that of MSSA (all P<0.05). The multidrug-resistant risk of MRSA (80.00%) was 12.36 times higher than that of MSSA (24.44%). Conclusions Multidrug-resistant SA especially MRSA strains isolated from newborns had the higher prevalence, the drugs resistance rate of MRSA strains was more serious than that of MSSA.
