Temporal and spatial distribution characteristics of NSCLP in Gansu Province from 2010 to 2016
10.16462/j.cnki.zhjbkz.2019.09.017
- Author:
Jie LEI
1
;
Jing-yan YUAN
;
Xi SHEN
;
Si-xuan ZHAO
;
Rui-min LIU
;
Lan YANG
;
Hong-liang DU
;
Xiao-dong XIE
Author Information
1. Life Science School of Lanzhou University, Lanzhou 730000, China
- Publication Type:Research Article
- Keywords:
NSCLP;
GIS;
Space-time clustering
- From:
Chinese Journal of Disease Control & Prevention
2019;23(9):1102-1106
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the temporal and spatial distribution characteristics of non-syndromic cleft lip with or without palate (NSCLP) who born in Gansu Province from 2010 to 2016, and to establish a predictive model for developing the strategies for the prevention and control of NSCLP. Methods Spatial epidemiological research method and geographical information systems (GIS) were used to conduct thematic mapping, spatial correlation analysis, high/low clustering analysis, hotspot analysis and Kirging interpolation prediction for NSCLP patients in Gansu Province from 2010 to 2016. Results From 2010 to 2016, the aggregation trend of NSCLP incidence in 89 counties in Gansu Province was different obviously, the southeast area was high and the northwest was low. Based on the data of the cumulative incidence of NSCLP from 2010 to 2016 in Gansu, the spatial distribution of NSCLP presented positive spatial correlation (Moran’I=0.274,Z=7.814,P<0.001) and the aggregation type was high-high cluster(Getis Gi=0.000 003,Z=4.381,P<0.001), with 22 hot spots. The Kirging interpolation prediction results showed that the main prevalence trend of NSCLP in Gansu extended from Longdong to Longxi and Longnan areas. Conclusions The geographical distribution of NSCLP had a positive spatial correlation and a high-high aggregation type in Gansu from 2010 to 2016. The high aggregation area is concentrated in Longdong, Longxi and Longnan of Gansu, which suggest that it is essential to focus on prevention and control in these areas.