A prospective study on the association between body mass index and all-cause mortality in type 2 diabetic patients
10.16462/j.cnki.zhjbkz.2019.08.012
- Author:
Ying LI
1
;
Jian SU
;
Hao YU
;
Yu QIN
;
Peng-fei LUO
;
En-chun PAN
;
Ning ZHANG
;
Chong SHEN
;
Jin-yi ZHOU
;
Ming WU
Author Information
1. School of Public Health, Southeast University, Nanjing 210009, China
- Publication Type:Research Article
- Keywords:
Body mass index;
Death risk;
Diabetes mellitus;
Cohort study
- From:
Chinese Journal of Disease Control & Prevention
2019;23(8):945-950
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim is to investigate the association between body mass index (BMI) and risk of all-cause mortality among patients with type 2 diabetes. Methods A total of 17 638 patients with type 2 diabetes registered in the management of National Basic Public Health Services in two areas of southern and northern Jiangsu were recruited. Cox proportional risk regression model was used to calculate the hazard ratio(HR) value and 95% confidence interval (95% CI) of different BMI groups in the follow-up period. Results The subjects were followed up for a total of 77 451 person-years with an average duration of 4.39 years, and 1 274 patients died during the follow-up period. The number of death in low weight group (BMI<18.5 kg/m2), normal weight group (18.5 kg/m2≤BMI<24 kg/m2), overweight (24 kg/m2≤BMI<28 kg/m2) and obese group (BMI≥28 kg/m2) were 39, 575, 484 and 176 respectively.The corresponding mortalities were 15.6%, 9.5%, 6.2% and 5.1%, respectively. Compared to normal weight group, the adjusted HR of all-cause mortality in low weight, overweight and obese group were 1.66 (95% CI: 1.20-2.30), 0.68 (95% CI: 0.61-0.77), 0.58 (95% CI: 0.48-0.68), respectively. Conclusions Low-weight patients have the highest risk of all-cause mortality compared with normal counterparts, while both overweight and obese people have a lower risk of death. Overweight and obesity may reduce the risk of all-cause mortality in type 2 diabetic patients.
