Associations between sleep duration and different ischemic stroke subtypes
10.16462/j.cnki.zhjbkz.2019.07.010
- Author:
Man LI
1
;
Yao WU
;
Yao-hua TIAN
;
Ya-ying CAO
;
Zhe HUANG
;
Shao-ping HUANG
;
Xiao-fen LIU
;
Xue-ying QIN
;
Xun TANG
;
Jin LI
;
Tao WU
;
Da-fang CHEN
;
Bei-bei XU
;
Yong-hua HU
Author Information
1. Department of Epidemiology and Biostatistics，School of Public Health，Peking University, Beijing 100191, China
- Publication Type:Research Article
- Keywords:
Sleep duration;
Ischemic stroke;
Subtype;
Risk factors
- From:
Chinese Journal of Disease Control & Prevention
2019;23(7):790-795
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between sleep duration and different ischemic stroke (IS) subtypes. Methods Participants in the study were recruited from rural communities in Beijing. The survey questionnaires, physical examination and biochemical tests were performed. Sleep duration was categorized into 5 groups, namely ≤5 hours/day, 6 hours/day (5.5-6.5 h/d), 7 hours/day (6.5-7.5 h/d), 8 hours/day (7.5-8.5 h/d) and ≥9 hours/day(≥8.5 h/d). Classification of ischemic stroke was based on Trial of org 10172 in acute stroke treatment(TOAST)classification. Logistic models were used to evaluate the associations between sleep duration and different IS subtypes. Results A total of 6 370 participants were recruited. The average age was (58.34±9.37) years old. Logistic regression analysis showed that after adjusting for age, sex, behavioral lifestyle, socioeconomic status and health status, compared to subjects with 7 hours/day, subjects with sleep duration ≤5 hours/day was significantly associated with increased risk of IS (OR=1.75, 95% CI: 1.42-2.15, P<0.001), large-artery atherosclerosis (OR=1.98, 95% CI:1.46-2.70, P<0.001), small-artery occlusion lacunar (OR=5.73, 95% CI:3.34-9.83, P<0.001) and stroke of undetermined etiology (OR=4.43, 95% CI:1.86-10.53, P=0.001). Subjects with sleep duration 8 hours/day and ≥9 hours/day was only found to be significantly associated with IS and large-artery atherosclerosis (P<0.05). Conclusions Short sleep duration is associated with increased risk of IS, large-artery atherosclerosis, small-artery occlusion lacunar and stroke of undetermined etiology. But long sleep duration is only associated with increased risk of IS and large-artery atherosclerosis.
