One new truxillic amide compound from Abrus mollis leaves
10.16438/j.0513-4870.2016-0545
- VernacularTitle:毛鸡骨草叶中一个新的吐昔酰胺类成分
- Author:
Xu-jiang YUAN
1
;
Ping ZHANG
1
;
Chun-yang LI
1
;
Wu-zhen HUO
1
;
Xiang-e LU
1
;
Yan-hong WU
1
Author Information
1. Research and Development Institute of Chinese Materia Medica, Guangdong Pharmaceutical University/Class III Laboratory of Modern Chinese Medicine Preparation, State Administration of Traditional Chinese Medicine of the P. R. C., Guangzhou 510006, China
- Publication Type:ORIGINAL ARTICLES
- Keywords:
Abrus mollis Hance;
chemical constituent;
abrusamide C;
amide
- From:
Acta Pharmaceutica Sinica
2016;51(10):1595-
- CountryChina
- Language:Chinese
-
Abstract:
The butanol extract part was extracted and isolated with water, alcohol and different organic solvents from Abrus mollis leaves. 6 compounds were isolated and purified using various column chromatographies and identified with the spectral techniques such as UV, MS, TLC, HPLC and NMR. The structures of 6 compounds were trigonelline (1), praline (2), alanine anhydride (3), (Z)-N-(4-hydroxycinnamoyl)tyrosine (4), (E)-N-(4-hydroxycinnamoyl)tyrosine (5), and abrusamide C (6). Compound 6 is a new compound, and compounds 1-4 were isolated from the plant for the first time.
