A case of membranous glomerulonephritis induced by lithium.
- Author:
Sung Tae CHO
1
;
Jin Seok KO
;
In Sang YOON
;
Jin Cheol KIM
;
Rho Won CHUN
;
Jung Woo NOH
;
Eun Sook NAM
Author Information
1. Department of Internal Medicine, College of Medicine, Hallym University, Chunchon, Korea. jwn8671@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Lithium;
Nephrotic syndrome;
Membranous glomerulonephritis
- MeSH:
Adult;
Biopsy;
Bipolar Disorder;
Diabetes Insipidus, Nephrogenic;
Female;
Glomerulonephritis, Membranous*;
Humans;
Lithium Carbonate;
Lithium*;
Nephrotic Syndrome;
Proteinuria
- From:Korean Journal of Medicine
2002;63(6):682-687
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The lithium is widely employed as a psychotropic agent, specially in manic illness. Lithium nephrotoxicity can be divided into three main categories: nephrogenic diabetes insipidus, acute intoxication, chronic nephropathy including interstitial nephropathy and glomerulopathy manifested as nephrotic syndrome. But, nephrotic syndrome induced by lithium is very rare. We reported a nephrotic syndrome induced by lithium in a 27-year-old woman who was taking lithium carbonate for 11 years due to bipolar disorder. Renal biopsy showed membranous nephropathy. After withdrawal of lithium, clinical symptoms and proteinuria significantly improved.
