Research progress in mechanism of intestinal microorganisms in human diseases
10.16438/j.0513-4870.2015-0803
- VernacularTitle:肠道菌群与人体疾病发病机制的研究进展
- Author:
Zhang LIN
1
;
Xian-peng ZU
2
;
Hai-sheng XIE
3
;
Hui-zi JIN
1
;
Niao YANG
2
;
Xin-ru LIU
2
;
Wei-dong ZHANG
1
Author Information
1. School of Pharmacy, Shanghai Jiaotong University, Shanghai 200240, China
2. School of Pharmacy, Second Military Medical University, Shanghai 200433, China
3. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China
- Publication Type:REVIEWS
- Keywords:
gut microbiota;
metagenomics;
metabolic disease;
gastrointestinal disease;
behavior and cognitive disorder;
cancer;
autoimmune disease
- From:
Acta Pharmaceutica Sinica
2016;51(6):843-
- CountryChina
- Language:Chinese
-
Abstract:
The international cooperated research projects of the Human Microbiome Project (HMP) and Metagenomics of The Human Intestinal Tract (MetaHIT) were officially launched in 2007, which indicated the era of metagenomics research of microorganisms in human gastrointestinal tract had been coming. Each human body is a superorganism which is composed of 90% commensal microorganisms, especially the intestinal microorganisms. The intestinal microorganisms play an important role on health maintenance since they are involved in the absorption and metabolism of nutrients in the human bodies. Herein, we review the research progress in the mechanism of intestinal microorganisms in human diseases. Our purpose is to provide novel ideas on human health and therapeutic targets of diseases.
