Herpetolide C: one new 7H-dibenzoc,eoxepin-5-one from Herpetospermum caudigerum
10.16438/j.0513-4870.2015-0938
- VernacularTitle:波棱内酯Ⅲ:藏药波棱瓜子中分离到的一个新的联芳基七元内酯类化合物
- Author:
Xu-dong FAN
1
;
Guo-wei WANG
1
;
Hong WANG
1
;
Jing-xin MAO
1
;
Xiao-zhong LAN
2
;
Zhi-hua LIAO
3
;
Min CHEN
1
Author Information
1. SWU-TAAHC Medicinal Plant R & D Center, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China
2. TAAHC-SWU Medicinal Plant R & D Center, Agriculture and Animal Husbandry College, Tibet University, Nyingchi 860000, China
3. School of Life Sciences, Southwest University, Chongqing 400715, China
- Publication Type:ORIGINAL ARTICLES
- Keywords:
Herpetospermum caudigerum;
Cucurbitaceae;
herpetolide C
- From:
Acta Pharmaceutica Sinica
2016;51(5):770-
- CountryChina
- Language:Chinese
-
Abstract:
The chemical constituents of Herpetospermum caudigerum were investigated using chromatographic methods, including silica gel column chromatography, Sephadex LH-20 and semi-preparative HPLC. Four compounds were isolated and their structures were elucidated by spectral data and physicochemical properties, which were identified as 2,11-dimethoxy-3,9-dihydroxy-7H-dibenzo[c,e]oxepin-5-one (1), 7,8'-didehydroherpetotriol (2), herpetotriol (3) and kaempferitrin (4). Among those, compound 1 is one new 7H-dibenzo[c,e] oxepin-5-one, named as herpetolide C.
