Advances in the study of anti-MRSA natural products
10.16438/j.0513-4870.2015-0776
- VernacularTitle:抗耐甲氧西林金葡菌(MRSA)天然产物研究进展
- Author:
Hao SONG
1
;
Yong QIN
1
Author Information
1. West China School of Pharmacy, Sichuan University, Chengdu 610041, China
- Publication Type:REVIEWS
- Keywords:
anti-MRSA activity;
natural product;
medicinal chemistry
- From:
Acta Pharmaceutica Sinica
2016;51(5):698-
- CountryChina
- Language:Chinese
-
Abstract:
Methicillin-resistant Staphylococcus aureus (MRSA) is a multi-drug resistant pathogenic bacteria, which has seriously threatened human health for a long time. Discovery of novel anti-MRSA lead compounds with high efficiency and low toxicity represents an important research focus in the realm of antibiotic studies. Owing to their structural diversity and complexity, natural products have exhibited unique advantages and great potential in the development of anti-MRSA new drugs. This review summarizes the studies of anti-MRSA natural products and their relevant medicinal chemistry reported since 2010.
