Progress in the study of signal pathways for chronic inflammation-associated pancreatic carcinogenesis
10.16438/j.0513-4870.2015-0625
- VernacularTitle:慢性胰腺炎恶性转化的相关信号通路研究进展
- Author:
Qian-qian XU
1
;
Zhong-shi ZHOU
1
;
Ming XIANG
1
Author Information
1. School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
- Publication Type:REVIEWS
- Keywords:
chronic pancreatitis;
pancreatic carcinogenesis;
etiopathogenesis;
important pathogenesis related signal pathway;
non-coding RNA
- From:
Acta Pharmaceutica Sinica
2016;51(2):174-
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer is one of the most lethal and intractable human malignancies with poor prognosis. Chronic pancreatitis is the independent risk factor for pancreatic cancer. Smoking, obesity and family history are the risk factors for chronic inflammation-associated pancreatic carcinogenesis. Recent studies of signal pathways have made a significant progress in our understanding of chronic pancreatitis in pancreatic cancer. This review summarizes recent development in the important signal pathways involved in pancreatic carcino-genesis from chronic pancreatitis.
