Autoimmune hepatitis-related autoantibodies and their clinical significance
10.3969/j.issn.1001-5256.2019.06.048
- VernacularTitle:自身免疫性肝炎相关自身抗体及临床意义
- Author:
Mei XUE
1
;
Yi SHEN
;
Mengyi SHEN
Author Information
1. Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, China
- Publication Type:Research Article
- Keywords:
hepatitis, autoimmune;
autoantibodies;
review
- From:
Journal of Clinical Hepatology
2019;35(6):1392-1396
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune hepatitis (AIH) is an autoimmune response-mediated liver parenchymal inflammation targeting hepatocytes, with the features of autoantibodies in serum, a high serum level of immunoglobulin G, and/or hypergammaglobulinemia. Most AIH patients have one or more autoantibodies in serum, and these antibodies are important features of AIH and the basis for the diagnosis of AIH. Some antibodies are also associated with the clinical manifestations, disease activity, therapeutic response, and prognosis of AIH. This article reviews AIH-related autoantibodies and their clinical significance.
