Characteristics and mechanism of virological and liver function changes in pregnant women with chronic hepatitis B virus infection during pregnancy and after delivery
10.3969/j.issn.1001-5256.2019.06.038
- VernacularTitle:慢性HBV感染孕妇妊娠期及分娩后病毒学和肝功能变化的特点及机制
- Author:
Mengyu ZHAO
1
;
Huaibin ZOU
;
Yu CHEN
Author Information
1. Intractable Hepatic Diseases and Artificial Liver Treatment & Training Center, Beijing YouAn Hospital & Beijing Municipal Key Laboratory of Liver Failure and Artificial Liver Treatment Research, Capital Medical University, Beijing 100069, China
- Publication Type:Research Article
- Keywords:
hepatitis B virus;
pregnant woman;
virology;
liver function;
review
- From:
Journal of Clinical Hepatology
2019;35(6):1353-1357
- CountryChina
- Language:Chinese
-
Abstract:
In pregnant women with hepatitis B virus (HBV) infection, body changes (hormone levels and immune status) during pregnancy or drug withdrawal after antiviral therapy may lead to virological changes, abnormal liver function, and even adverse outcomes in severe cases. Therefore, strengthening the monitoring of virological indicators and liver function in pregnant women with chronic HBV infection during pregnancy and after delivery can help to find body changes in time and thus prevent the adverse outcomes such as hepatitis and liver failure. This article reviews the articles on the characteristics and mechanisms of virological and liver function changes in pregnant women with chronic HBV infection during pregnancy and after delivery, in order to provide theoretical support for clinicians on the management of pregnant women with chronic HBV infection during pregnancy and after delivery.
