Research advances in the pathogenesis of nonalcoholic fatty liver disease-related hepatocellular carcinoma
10.3969/j.issn.1001-5256.2019.07.043
- VernacularTitle:非酒精性脂肪性肝病相关肝细胞癌的发病机制
- Author:
Sutong LIU
1
;
Wenxia ZHAO
Author Information
1. Department of Hepatology and Spleen-Stomach, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China
- Publication Type:Research Article
- Keywords:
non-alcoholic fatty liver disease;
liver neoplasms;
pathologic processes
- From:
Journal of Clinical Hepatology
2019;35(7):1621-1625
- CountryChina
- Language:Chinese
-
Abstract:
The incidence rate of nonalcoholic fatty liver disease-related hepatocellular carcinoma (NAFLD-HCC) is gradually increasing. Its pathogenesis is associated with the changes in genetic and epigenetic modifications, metabolism, immunity, intestinal microecology, endocrine pathways, and circadian rhythm. This article summarizes the available data on the pathogenesis of NAFLD-HCC and points out that HCC is caused by the interactions between multiple factors.
