Influence of HBV DNA load on surgical outcome of hepatitis B-associated liver cancer
10.3969/j.issn.1001-5256.2018.09.035
- VernacularTitle:HBV DNA载量对乙型肝炎相关肝癌手术治疗效果的影响
- Author:
Haiwen YE
1
;
Yong DENG
;
Lingqiang ZHANG
Author Information
1. Graduate School of Qinghai University, Xining 810000, China
- Publication Type:Research Article
- Keywords:
viral load;
hepatitis B;
liver neoplasms;
surgical procedures, operative;
treatment outcome
- From:
Journal of Clinical Hepatology
2018;34(9):1995-1998
- CountryChina
- Language:Chinese
-
Abstract:
HBV infection is highly prevalent in China, and patients with a high HBV-DNA load for a long time may progress to liver cirrhosis, which may lead to liver cancer. At present, surgery is still the main method for the treatment of hepatitis B-related liver cancer. Many studies have shown that HBV DNA load is an important influencing factor for the recovery of liver function after surgery, postoperative complications, recurrence of liver cancer, and the success of liver transplantation in patients with hepatitis B-related liver cancer. Its mechanism may be associated with high HBV DNA load and HBV reactivation. Maintaining a low HBV DNA load by antiviral therapy can improve the prognosis of patients with hepatitis B-related liver cancer. This article reviews the influence of HBV DNA load before and after surgery on the surgical outcome of hepatitis B-related liver cancer, in order to provide a reference for research on the treatment of patients with liver cancer.
