Advances in research hotspots in liver failure complicated by acute kidney injury
10.3969/j.issn.1001-5256.2018.09.004
- VernacularTitle:肝衰竭并发急性肾损伤热点研究新进展
- Author:
Yan ZHUANG
1
;
Qing XIE
Author Information
1. Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
- Publication Type:Research Article
- Keywords:
liver failure;
renal insufficiency, acute;
diagnosis;
therapeutics;
biological markers
- From:
Journal of Clinical Hepatology
2018;34(9):1836-1841
- CountryChina
- Language:Chinese
-
Abstract:
Acute kidney injury (AKI) is defined as a sharp drop in glomerular filtration rate (GFR) and a rapid increase in serum creatinine and is one of the most serious complications of liver failure. Early diagnosis and treatment play a vital role in reducing the mortality and improving the prognosis of liver failure. This article elaborates on the research advances in the diagnostic criteria, pathogenesis, biomarkers, clinical features, and treatment of AKI and points out that constant modification of the definition and staging of AKI and research and development of efficient biomarkers for AKI are future research directions.
