Dual role of autophagy in hepatitis B virus and related liver diseases
10.3969/j.issn.1001-5256.2018.10.034
- VernacularTitle:自噬在HBV及相关肝脏疾病中的双重作用
- Author:
Jiali PENG
1
;
Xin LAI
;
Jia WEI
Author Information
1. Department of Hepatology, The Fourth Affiliated Hospital of Kunming Medical University, Kunming 650021, China
- Publication Type:Research Article
- Keywords:
autophagy;
hepatitis B virus;
hepatitis B，chronic;
liver cirrhosis;
carcinoma，hepatocellular;
review
- From:
Journal of Clinical Hepatology
2018;34(10):2217-2220
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a process of lysosome degradation and has a dual role in the development and progression of diseases, i.e., it can promote cell survival and induce cell death. This article introduces the dual role of autophagy in hepatitis B virus (HBV), chronic hepatitis B, liver fibrosis, and hepatocellular carcinoma and the mechanism of action of autophagy in related liver diseases. It is pointed out that autophagy may be a future research direction for the treatment of HBV-related liver diseases and can provide new ideas for the treatment of liver fibrosis and hepatocellular carcinoma.
