Research advances in immunotherapy for liver metastasis of pancreatic cancer
10.3969/j.issn.1001-5256.2018.11.044
- VernacularTitle:胰腺癌肝转移免疫治疗的研究进展
- Author:
Tianqiang JIN
1
;
Feng XU
;
Chaoliu DAI
Author Information
1. Department of Hepatobiliary and Splenic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China
- Publication Type:Research Article
- Keywords:
pancreatic neoplasms;
liver neoplasms;
neoplasm metastasis;
immunotherapy;
review
- From:
Journal of Clinical Hepatology
2018;34(11):2469-2474
- CountryChina
- Language:Chinese
-
Abstract:
Patients with liver metastasis of pancreatic cancer have poor prognosis and few opportunities for surgery, and conventional radiochemotherapy lacks a satisfactory effect. As a new therapeutic strategy for tumor, immunotherapy fights against cancer by enhancing patients′ immune function and may thus become an effective treatment regimen for liver metastasis of pancreatic cancer. This article reviews the latest research advances in immunotherapy for liver metastasis of pancreatic cancer from the aspects of immunomodulator, monoclonal antibody, immune checkpoint inhibitor, adoptive cellular immunotherapy, and tumor vaccine and points out that a combined treatment regimen has a promising future in clinical application.
