Research advances in drugs for the prevention and treatment of gallstones
10.3969/j.issn.1001-5256.2018.11.041
- VernacularTitle:药物防治胆囊结石研究进展
- Author:
Jingchang XU
1
;
Hui YE
;
Dasong WANG
Author Information
1. Department of Biliary Surgery, West China Hospital of Sichuan University, Chengdu 610041, China
- Publication Type:Research Article
- Keywords:
cholecystolithiasis;
drug therapy;
review
- From:
Journal of Clinical Hepatology
2018;34(11):2453-2457
- CountryChina
- Language:Chinese
-
Abstract:
The treatment of gallstones mainly relies on surgery and endoscopy, and in recent years, a large number of studies have proposed new ideas and thoughts for drugs in the prevention and treatment of gallstones. This article summarizes the efficacy and safety of bile acid drugs, statins, ezetimibe, and drugs acting on specific nuclear receptors involved in cholesterol and bile acid homeostasis, which have entered the clinical trial stage, in preventing and treating gallstones. It is pointed out that certain drugs and molecular sites may have some clinical effects in the prevention and treatment of gallstones, which provides a basis for developing individualized strategies for the prevention and treatment of gallstones with drugs.
