Diagnosis and treatment of pre-hepatic (sinusoidal) non-cirrhotic portal hypertension and related difficulties
10.3969/j.issn.1001-5256.2019.01.002
- VernacularTitle:肝（窦）前型非肝硬化门静脉高压症的诊断与治疗及其面临的困境
- Author:
Hangfei XU
1
;
Huiguo DING
Author Information
1. Center of Hepatic and Digestive Diseases, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
- Publication Type:Research Article
- Keywords:
hypertension, portal;
diagnosis;
therapy
- From:
Journal of Clinical Hepatology
2019;35(1):13-17
- CountryChina
- Language:Chinese
-
Abstract:
Pre-hepatic (sinusoidal) non-cirrhotic portal hypertension is a group of vascular heterogeneous diseases with portal hypertension as the prominent manifestation and has a complex etiology. Compared with the patients with cirrhotic portal hypertension, the patients with pre-hepatic (sinusoidal) non-cirrhotic portal hypertension have normal liver functions, normal or a mild increase in hepatic venous pressure gradient, and better prognosis. Pre-hepatic (sinusoidal) non-cirrhotic portal hypertension may easily be misdiagnosed as unexplained cirrhotic portal hypertension, and liver pathology is the gold standard for diagnosis. Non-selective β-receptor blockers and endoscopy are major therapies for this disease, but there is a lack of high-quality clinical evidence from large-scale prospective multicenter studies.
