The association between interleukin-8 and autoimmune liver diseases
10.3969/j.issn.1001-5256.2019.02.039
- VernacularTitle:IL-8与自身免疫性肝病的关系
- Author:
Yunjie LEI
1
;
Jinhui YANG
Author Information
1. Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China
- Publication Type:Research Article
- Keywords:
interleukin-8;
hepatitis, autoimmune;
primary biliary cholangitis;
primary sclerosing cholangitis;
review
- From:
Journal of Clinical Hepatology
2019;35(2):411-413
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin-8 (IL-8) is an inflammatory cytokine with chemotaxis and there is a significant increase in the expression of IL-8 in autoimmune liver diseases. It participates in disease progression by binding to its receptors CXCR1 and CXCR2, promoting chemotaxis of inflammatory cells, angiogenesis, and fibrosis, and inducing cell proliferation. This article reviews the research advances in the association between IL-8 and autoimmune liver diseases.
