Research advances in the role of lipid metabolism in hepatitis C virus infection and life cycle
10.3969/j.issn.1001-5256.2019.02.035
- VernacularTitle:脂质代谢在HCV感染及生命周期中的作用
- Author:
Chu XU
1
;
Pingan ZHANG
Author Information
1. Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, China
- Publication Type:Research Article
- Keywords:
hepacivirus;
lipid metabolism;
review
- From:
Journal of Clinical Hepatology
2019;35(2):395-398
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis C virus (HCV) infection is one of the leading causes of liver cirrhosis, end-stage liver disease, and even liver cancer. Patients with HCV infection tend to have insulin resistance and dyslipidemia, which may lead to a series of metabolic syndromes and greatly threaten human health. At present, there are still no effective vaccines to prevent HCV infection, and therefore, the mechanism of HCV infection remains a hot topic in clinical research. Many studies have shown that there is a complex relationship between HCV infection and lipids, but the role of lipids in HCV infection remains unclear. This article reviews the current research status of the role of lipid metabolism in HCV infection and life cycle, in order to understand the mechanism of abnormal fat metabolism in the liver and the pathogenesis of fatty liver disease.
