Research advances in the pathogenesis and diagnosis/treatment of muscle injury after treatment with nucleos(t)ide analogues in patients with chronic hepatitis B
10.3969/j.issn.1001-5256.2019.03.039
- VernacularTitle:慢性乙型肝炎患者核苷（酸）类似物治疗后相关肌损伤的发病机制及诊疗进展
- Author:
Ling YUAN
1
;
Baimei ZENG
;
Shide LIN
Author Information
1. Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou 563003, China
- Publication Type:Research Article
- Keywords:
hepatitis B, chronic;
nucleosides;
nucleotides;
muscle injury;
review
- From:
Journal of Clinical Hepatology
2019;35(3):627-630
- CountryChina
- Language:Chinese
-
Abstract:
With the wide application of nucleos(t)ide analogues (NAs) in antiviral therapy for chronic hepatitis B (CHB), the side effects of NAs after long-term use have attracted more and more attention from clinicians and patients. In recent years, an increasing number of studies have reported muscle injury in CHB patients treated with NAs, and we have gained a deeper understanding of the incidence rate, pathogenesis, and treatment of muscle injury. This article reviews the incidence rate, related factors, clinical manifestations, pathogenesis, management, and prevention and treatment of muscle injury associated with NAs.
