Current status of research on bile duct lesions and related liver diseases
10.3969/j.issn.1001-5256.2019.04.051
- VernacularTitle:胆管病变及其相关肝脏疾病的研究现状
- Author:
Jiamin XU
1
;
Yingmei TANG
Author Information
1. Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China
- Publication Type:Research Article
- Keywords:
bile duct diseases;
liver diseases;
review
- From:
Journal of Clinical Hepatology
2019;35(4):934-
- CountryChina
- Language:Chinese
-
Abstract:
The bile duct is the channel for bile transport in the liver, and the lining epithelial cells in the bile duct have functional and morphological heterogeneity and are the target of various bile duct diseases. In addition to bile metabolism and secretion, biliary epithelial cells are also involved in tissue damage and repair. Biliary epithelial cells have an immune barrier function and can secrete different proinflammatory factors and chemokines. Under the stimulation of endogenous and exogenous factors, biliary epithelial cells present immune reactivity and initiate immune response in the host. This article reviews the current status of research on bile duct lesions and related liver diseases.
