Application and management of autologous bone marrow stem cells in treatment of liver cirrhosis
10.3969/j.issn.1001-5256.2019.04.042
- VernacularTitle:自体骨髓干细胞治疗肝硬化的应用及管理
- Author:
Deng WANG
1
;
Hang SUN
;
Chuanxin WU
Author Information
1. Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
- Publication Type:Research Article
- Keywords:
liver cirrhosis;
bone marrow transplantation;
therapeutics;
review
- From:
Journal of Clinical Hepatology
2019;35(4):895-898
- CountryChina
- Language:Chinese
-
Abstract:
Liver transplantation is considered the best method for the treatment of liver cirrhosis, but its clinical application is limited by the shortage of liver donors, high costs, and immunological rejection. In recent years, bone marrow stem cells (BMSCs) has shown great prospects in the treatment of liver cirrhosis. Recent clinical studies have shown that BMSC therapy is a safe and effective treatment method for liver cirrhosis, but its mechanism remains unclear, and there are various treatment regimens. This article reviews the mechanism of BMSCs in the treatment of liver cirrhosis, route of BMSC delivery, indices for therapeutic effect evaluation, and dose of BMSCs.
