Assessment and clinical management of sarcopenia in patients with liver cirrhosis
10.3969/j.issn.1001-5256.2019.04.041
- VernacularTitle:肝硬化患者肌少症的评估与临床管理
- Author:
Fang HAN
1
;
Tao HAN
;
Jing LIANG
Author Information
1. Department of Hepatology, Tianjin Third Central Hospital, Tianjin 300170, China
- Publication Type:Research Article
- Keywords:
liver cirrhosis;
muscular disorders, atrophic;
muscle, skeletal;
review
- From:
Journal of Clinical Hepatology
2019;35(4):891-894
- CountryChina
- Language:Chinese
-
Abstract:
As the disease progresses, there is a significant change in the body composition of patients with liver cirrhosis, and sarcopenia is one of the common complications in liver cirrhosis, especially in decompensated cirrhosis. About 30%-70% of patients with liver cirrhosis have sarcopenia, which greatly affects patients’ survival and is closely associated with the development of hepatic encephalopathy. Sarcopenia may also increase the risk of infection. Sarcopenia and muscle fatty degeneration can be used as poor prognostic indicators of hepatocellular carcinoma and may increase the risk of recurrence of liver cancer. This article reviews the research advances in the definition of sarcopenia, the association of sarcopenia with liver cirrhosis, and assessment and clinical management of sarcopenia.