The era of the reversal of liver fibrosis and cirrhosis: Current status and challenges
10.3969/j.issn.1001-5256.2019.04.001
- VernacularTitle:肝纤维化和肝硬化逆转的时代：现状与挑战
- Author:
Bingqiong WANG
1
;
Yameng SUN
;
Hong YOU
Author Information
1. Liver Research Center, Beijing Friendship Hospital, Capital Medical University & National Clinical Research Center for Digestive Diseases, Beijing 100050, China
- Publication Type:Research Article
- Keywords:
liver cirrhosis;
biological markers;
biopsy;
editorial
- From:
Journal of Clinical Hepatology
2019;35(4):705-708
- CountryChina
- Language:Chinese
-
Abstract:
An increasing number of clinical studies have shown that effective etiological therapy might achieve the reversal of liver fibrosis/early cirrhosis. An accurate assessment of fibrosis reversal is of great importance for treatment decision-making and prognosis prediction. At present, the “gold standard” for the histological evaluation of liver fibrosis/cirrhosis reversal remains to be perfected, and there is still a controversy over the noninvasive assessment of fibrosis reversal. Long-term cohort studies are needed to observe whether it can improve clinical hard endpoint, and the clinical effect of new anti-fibrotic drugs needs to be further confirmed.
