Role of autoimmune ecological factors in the pathogenesis of autoimmune hepatitis
10.3969/j.issn.1001-5256.2019.10.046
- VernacularTitle:自身免疫生态学因素在自身免疫性肝炎发病机制中的作用
- Author:
Jie CHEN
1
;
Chunyang HUANG
;
Jing SHAN
Author Information
1. Department of Hepatology and Immunology, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
- Publication Type:Research Article
- Keywords:
hepatitis, autoimmune;
enviromental exposure;
ecologys
- From:
Journal of Clinical Hepatology
2019;35(10):2339-2341
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune hepatitis (AIH) is a chronic liver inflammatory disease with unknown etiology, and at present, both genetic and environmental factors are thought to be involved in the pathogenesis of AIH. Environmental exposure has an important impact on the development of AIH. Autoimmune ecology is the study of the interactions between individuals and their environment, the development of imbalance between individuals and environment, and the mechanism of such imbalance in promoting the development of autoimmune disease. This article reviews the research advances in the role of autoimmune ecology in the pathogenesis of AIH.