Clinical significance and application of quantification of hepatitis B core antibody
10.3969/j.issn.1001-5256.2019.10.005
- VernacularTitle:抗-HBc定量的临床意义与应用
- Author:
Xueru YIN
1
;
Gexin SHE
;
Jinlin HOU
Author Information
1. Hepatology Unit and Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China)
- Publication Type:Research Article
- Keywords:
hepatitis B virus;
hepatitis B antibodies;
infectious disease transmission, vertical
- From:
Journal of Clinical Hepatology
2019;35(10):2156-2158
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B virus (HBV) infection is a global public health problem. Hepatitis B core antibody (anti-HBc) is one of the serum immunological markers in human body after HBV infection. Previous studies have shown that the low serum level of anti-HBc in HBeAg-positive mothers are associated with immunoprophylaxis failure in infants. In addition, anti-HBc is an important biomarker associated with liver inflammatory activity and therapeutic outcome and can be used to evaluate liver inflammation and predict the efficacy of antiviral therapy and sustained response after drug withdrawal. Anti-HBc quantification provides a new direction for individualized treatment of hepatitis B patients.
