Current status of associating liver partition and portal vein ligation for staged hepatectomy in treatment of liver metastasis of colorectal cancer
10.3969/j.issn.1001-5256.2019.12.035
- VernacularTitle:联合肝脏离断和门静脉结扎二步肝切除术治疗结直肠癌肝转移的研究现状
- Author:
Yang LIAO
1
;
Shengwei LI
Author Information
1. Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
- Publication Type:Research Article
- Keywords:
colorectal neoplasms;
neoplasm metastasis;
hepatectomy
- From:
Journal of Clinical Hepatology
2019;35(12):2805-2808
- CountryChina
- Language:Chinese
-
Abstract:
At present, radical resection remains the best treatment strategy for liver metastasis of colorectal cancer, and patients with large or multiple tumors often face the problem of insufficient residual liver volume after hepatectomy, which may lead to serious complications including liver failure after surgery. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a novel two-step hepatectomy that allows rapid proliferation of the residual liver after primary surgery and can improve the resectability of liver tumors and reduce the risk of postoperative liver failure. Although ALPPS can achieve R0 resection or tumors and prolong patients’ survival time, there are still controversies over its application due to high incidence rates of complications and mortality rate. With reference to related studies in China and foreign countries, this article reviews the current application status and clinical value of ALPPS in liver metastasis of colorectal cancer.
