Liver transplantation for the treatment of intrahepatic cholangiocarcinoma: Controversies and perspectives
10.3969/j.issn.1001-5256.2019.12.006
- VernacularTitle:肝内胆管癌的肝移植治疗——争议与前景
- Author:
Hongtao ZHANG
1
;
Kaishan TAO
Author Information
1. Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi’an 710032, China
- Publication Type:Research Article
- Keywords:
bile duct neoplasms;
liver transplantation;
neoadjuvant therapy
- From:
Journal of Clinical Hepatology
2019;35(12):2644-2647
- CountryChina
- Language:Chinese
-
Abstract:
Liver transplantation is the only effective method for the treatment of end-stage liver disease, but there are still controversies over its application in the treatment of intrahepatic cholangiocarcinoma (ICC). ICC has a high degree of malignancy, occult symptoms, and a lack of specific clinical manifestations in the early stage. Most patients are in the advanced stage at the time of diagnosis and lose the opportunity for surgical resection, and thus they tend to have poor prognosis. With the research advances in liver transplantation for the treatment of ICC, development of standardized criteria for patient selection and combination with neoadjuvant therapy and adjuvant therapy may become a promising method for the treatment of locally advanced ICC.
