Research advances in association between diseases outside the gallbladder and gallstones
10.3969/j.issn.1001-5256.2016.05.050
- VernacularTitle:胆外疾病与胆囊结石相关性的研究进展
- Author:
Juan LI
1
;
Xiaoguo WEI
;
Qiming LU
Author Information
1. Department of Gastroenterology, Gansu Provincial People′s Hospital, Lanzhou 730000, China
- Publication Type:Research Article
- Keywords:
cholecystolithiasis;
metabolic syndrome X;
liver diseases;
gastrointestinal diseases;
enterobacteriaceae;
review
- From:
Journal of Clinical Hepatology
2016;32(5):1018-1021
- CountryChina
- Language:Chinese
-
Abstract:
Gallstones is a common digestive system disease in China and has a complex pathogenesis. It is often considered that it is mediated by many factors in the genetic background, including biliary cholesterol supersaturation, intestinal cholesterol hyperabsorption, abnormal cholesterol nucleation in bile, dysfunction in gallbladder dynamics, and cholestasis. This article reviews the role of the above mechanisms in the association between diseases outside the gallbladder and gallstones. Based on current evidence, the above diseases may promote the formation of gallstones, and active intervention of the above diseases outside the gallbladder may help to expand new strategies for the prevention and treatment of gallstones.