Clinical features of Crohn's disease in Korean patients residing in Busan and Gyeongnam.
- Author:
Eun Ji LEE
1
;
Tae Oh KIM
;
Geun Am SONG
;
Jong Hun LEE
;
Hyung Wook KIM
;
Sam Ryong JEE
;
Seun Ja PARK
;
Hyun Jin KIM
;
Jong Ha PARK
Author Information
- Publication Type:Original Article
- Keywords: Crohn disease; Inflammatory bowel diseases; Clinical features; Intestinal resection
- MeSH: Busan*; Colon; Colonic Diseases; Crohn Disease*; Diagnosis; Follow-Up Studies; Humans; Incidence; Inflammatory Bowel Diseases; Korea; Sex Distribution; Tertiary Healthcare
- From:Intestinal Research 2016;14(1):30-36
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Crohn's disease (CD) is a chronic inflammatory bowel disease that presents with variable features and repeated disease aggravation. The incidence of CD is increasing in Korea. We evaluated the clinical features of CD in a study population in Busan and Gyeongnam, Korea. METHODS: A hospital-based analysis included 619 patients diagnosed with CD between March 1986 and February 2013 from seven tertiary care hospitals in Busan and Gyeongnam. Individual case records were reviewed with regard to age at diagnosis, sex, disease location, disease behavior, and medical and surgical treatments received during the follow-up period. RESULTS: The cumulative frequency of patients diagnosed with CD revealed a continued increase in the number of cases reported yearly. The male-to-female ratio was 2.5:1 and the median age at diagnosis was 24 years. At diagnosis, 114 (18.4%) had isolated small bowel disease, 144 (23.3%) had isolated colonic disease, and 358 patients (57.8%) presented with disease in the small bowel and colon. The number of patients presenting with stricturing or penetrating disease behavior was 291 (47%) at the final evaluation. In total, 111 (17.9%) patients underwent intestinal resections. CONCLUSIONS: A continued increase in the number of patients diagnosed with CD was found in Busan and Gyeongnam as observed in other regions. We report results similar to that of other Korean studies in terms of sex distribution, age, and location of disease.
