Renal safety in chronic hepatitis B patients treated with nucleos(t)ide analogues
10.3969/j.issn.1001-5256.2016.05.042
- VernacularTitle:核苷和核苷酸类药物治疗慢性乙型肝炎过程中肾脏的安全性问题
- Author:
Ling NING
1
;
Jian SUN
;
Nan CHEN
Author Information
1. Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
- Publication Type:Research Article
- Keywords:
hepatitis B, chronic；nucleosides；nucleotides;
therapy；review
- From:
Journal of Clinical Hepatology
2016;32(5):981-985
- CountryChina
- Language:Chinese
-
Abstract:
Nucleos(t)ide analogues (NAs) are commonly used as the antiviral treatment in patients with chronic hepatitis B (CHB). The majority of patients need long term medication. Renal injury has been observed in some patients treated with NAs in clinical practice. Therefore, this article reviews the issues regarding renal safety in CHB patients treated with NAs from the following aspects: the possible mechanisms of renal injury, the incidence of renal injury in patients treated with various NAs in recent clinical studies, and the management of renal injury in CHB patients, in order to select the most appropriate drugs for patients.
