A prognostic analysis of laparoscopic versus radical cholecystectomy for T1b unsuspected gallbladder carcinoma
10.3969/j.issn.1001-5256.2016.04.031
- VernacularTitle:单纯腹腔镜胆囊切除术与胆囊癌根治术治疗T1b期意外胆囊癌患者的预后比较
- Author:
Wenlong LIU
1
;
Bin LIANG
;
Yuanhu TIAN
Author Information
1. Chinese PLA General Hospital,Beijing 100853
- Publication Type:Research Article
- Keywords:
gallbladder neoplasms;
cholecystectomy;
prognosis
- From:
Journal of Clinical Hepatology
2016;32(4):754-757
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the surgical treatment and prognosis of T1b unsuspected gallbladder carcinoma (UGC). MethodsTwenty-two patients with T1b UGC admitted to our hospital were enrolled as subjects. The information on clinical pathology, radiological examination, laboratory tests, surgical treatment, and postoperative follow-up were analyzed in patients. The survival rate and recurrence were compared between patients treated with radical cholecystectomy and laparoscopic cholecystectomy. The Kaplan-Meier method was used to calculate survival rates, and the log-rank test was used for survival difference analysis. Comparison of categorical data was made by Fisher′s exact test. ResultsThe 1-, 3-, and 5-year accumulative survival rates in all patients with T1b UGC were 100%, 89.7%, and 82.8%, respectively; there was no significant difference in the 5-year accumulative survival rate between patients treated with laparoscopic cholecystectomy and radical cholecystectomy (84.6% vs 75.0%, χ2=0.000, P=0.991); two (15.4%) out of thirteen patients treated with laparoscopic cholecystectomy respectively; one (12.5%) out of eight patients treated with radical cholecystectomy had recurrence, there was no significant difference between the two groups(P＞005). ConclusionRadical cholecystectomy is a superior therapy for T1b UGC over laparoscopic cholecystectomy.
