Total laparoscopic hepatectomy versus open hepatectomy in treatment of hepatocellular carcinoma in the left lateral lobe: a case-matched analysis
10.3969/j.issn.1001-5256.2016.04.026
- VernacularTitle:完全腹腔镜与开腹肝术切除术治疗左外叶肝细胞癌的效果比较
- Author:
Yong XIONG
1
;
Hebin WANG
;
Deqin LIU
Author Information
1. Division of Hepatobiliary Pancreatic Surgery, Panzhihua Central Hospital, Panzhihua, Sichuan 617067, China
- Publication Type:Research Article
- Keywords:
carcinoma, hepatocellular;
laparoscopy;
hepatectomy;
comparative study
- From:
Journal of Clinical Hepatology
2016;32(4):735-738
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the safety, feasibility, and efficacy of total laparoscopic hepatectomy in the treatment of hepatocellular carcinoma (HCC) in the left lateral lobe. MethodsA case-matched analysis was performed between 25 patients with HCC in the left lateral lobe confirmed by postoperative pathological examination, who were admitted to Panzhihua Central Hospital and underwent total laparoscopic left lobe resection (LLLR) from April 2012 to April 2015, and 25 patients with HCC who underwent open left lobe resection (OLLR) during the same period. The t-test was used for comparison of continuous data between the two groups, and the chi-square test or Fisher′s exact test was used for comparison of catagorical data between the two groups; the Kaplan-Meier method was used for survival analysis, and the log-rank test was used for comparison of survival curves. ResultsThe time of operation, number of patients undergoing intraoperative blood transfusion, and number of patients with R0 resection margin showed no significant differences between the LLLR group and the OLLR group, but intraoperative blood loss (216.4±15.39 ml vs 273.2±16.65 ml), mean hospital stay (6.92±0.29 min vs 10.32±052 min), and postoperative complications (5 cases vs 12 cases) showed significant differences between the two groups (all P＜0.05). The 1- and 3-year overall survival rates and progression-free survival showed no significant differences between the LLLR group and the OLLR group. ConclusionLLLR and OLLR have similar long-term efficacy in the treatment of HCC in the left lateral lobe, and LLLR has advantages in the aspects of intraoperative blood loss, postoperative complications, and length of hospital stay.
