Application of magnetic resonance elastography as a non-invasive technique for diagnosis of liver fibrosis
10.3969/j.issn.1001-5256.2016.03.042
- VernacularTitle:磁共振弹性成像在肝纤维化无创诊断中的应用
- Author:
Minglei YANG
1
;
Dingkang YAO
Author Information
1. Department of Internal Medicine, Shanghai Changzheng Hospital, Shanghai 200003, China
- Publication Type:Research Article
- Keywords:
liver cirrhosis;
elasticity imaging techniques;
diagnosis;
review
- From:
Journal of Clinical Hepatology
2016;32(3):588-592
- CountryChina
- Language:Chinese
-
Abstract:
At present, liver biopsy is the gold standard for the diagnosis and grading of liver fibrosis, but its limitations have been widely acknowledged. The non-invasive detection methods are needed in clinical practice, and at present, magnetic resonance elastography (MRE) is a hot research topic. This article reviews the advances in the clinical application of MRE in related fields, and studies have shown that MRE has a high diagnostic value due to its high sensitivity and specificity in the diagnosis and grading of liver fibrosis and an area under the receiver operating characteristic curve as high as 0.95. Compared with serological and other imaging diagnostic methods, MRE can determine fibrosis stage more accurately and has good reproducibility and objectivity. MRE can be widely applied in all patients except those with hemochromatosis, with special advantages in the diagnosis for patients with obesity and ascites, and can make up for the disadvantages of other methods. This article points out that MRE may become the best non-invasive method for the assessment of liver fibrosis, especially advanced fibrosis.
