Research advances in natural drugs for prevention and treatment of nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2016.03.035
- VernacularTitle:天然药物防治非酒精性脂肪性肝病的研究进展
- Author:
Baoqing LIU
1
;
Xiuqin XU
;
Siye MEN
Author Information
1. Department of General Surgery, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China
- Publication Type:Research Article
- Keywords:
fatty liver;
drug therapy;
review
- From:
Journal of Clinical Hepatology
2016;32(3):557-560
- CountryChina
- Language:Chinese
-
Abstract:
At present, nonalcoholic fatty liver disease (NAFLD) is the most common liver disease, and is often regarded as the manifestation of metabolic syndrome in the liver. There are no specific drugs for this disease at the moment, and the only therapeutic method proved effective is guiding life style to reduce body weight. Insulin resistance, oxidative stress response, inflammatory response, and apoptosis are involved in the pathogenesis of NAFLD. Animal experiments and human studies have proved that various natural drugs have antioxidant, anti-inflammatory, or insulin-sensitizing effects and thus have significant efficacy in the treatment of NAFLD. This article summarizes the research advances in 10 natural drugs commonly used for the prevention and treatment of NAFLD in recent years and treatment of NAFLD in recent years and concludes that more studies are needed to confirm the efficacy of natural drugs in NAFLD patients.
