Research advances in non-hormonal therapies for autoimmune hepatitis
10.3969/j.issn.1001-5256.2016.02.040
- VernacularTitle:自身免疫性肝炎非激素疗法的研究进展
- Author:
Qihua ZHONG
1
;
Guiqin ZHOU
;
Xianbo WANG
Author Information
1. Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
- Publication Type:Research Article
- Keywords:
hepatitis, autoimmune；immunosuppressive agents;
TCM WM therapy;
review
- From:
Journal of Clinical Hepatology
2016;32(2):378-381
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune hepatitis is a chronic progressive inflammatory disease of the liver, which is mediated by the abnormal autoimmune response. Immunosuppressive therapy is the major therapeutic method for this disease, and liver transplantation can be performed for patients in the advanced stage. At present, the internationally acknowledged standard therapeutic method is prednisone or prednisone combined with azathioprine. Most patients can achieve clinical remission, but the recurrence rate is high and some patients fail to respond to the treatment. This article briefly reviews the therapies except corticosteroid therapy and substitutive therapy after treatment failure, introduces the application of integrated traditional Chinese and Western medicine therapy for autoimmune hepatitis, and points out that non-hormonal therapies are the new directions for the treatment of autoimmune hepatitis, which still needs to be further investigated.
