Research advances in association between regulatory T cells and hepatitis B virus infection
10.3969/j.issn.1001-5256.2016.02.036
- VernacularTitle:调节性T淋巴细胞与HBV感染慢性化的关系
- Author:
Junnan HE
1
;
Shousong ZHAO
Author Information
1. Department of Infectious Diseases, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233000, China
- Publication Type:Research Article
- Keywords:
hepatitis B, chronic;
T-lymphocytes, regulatory;
T-lymphocytes, helper-inducer;
review
- From:
Journal of Clinical Hepatology
2016;32(2):361-365
- CountryChina
- Language:Chinese
-
Abstract:
Regulatory T cells are a subset of T cells, and can inhibit the body′s immune response and induce immune tolerance, which has become one of the hot topics in the field of immunological research in recent years. Regulatory T cell dysfunction and the change in the number of regulatory T cells are closely associated with the progression and treatment of autoimmune diseases, infectious diseases, tumor immune tolerance, transplant rejection, and allergic diseases. This article summarizes the surface markers and immunological mechanism of regulatory T cells, as well as the association of regulatory T cells with the pathogenesis of hepatitis B and antiviral therapy.
