Application of tumor-associated antigens and their autoantibodies in early diagnosis of hepatocellular carcinoma
10.3969/j.issn.1001-5256.2016.07.047
- VernacularTitle:肿瘤相关抗原及其自身抗体在肝细胞癌早期诊断中的应用
- Author:
Ting WANG
1
;
Mei LIU
;
Lei DONG
Author Information
1. Artificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
- Publication Type:Research Article
- Keywords:
carcinoma, hepatocellular;
antigens, neoplasm;
antibodies, neoplasm;
early diagnosis;
review
- From:
Journal of Clinical Hepatology
2016;32(7):1418-1421
- CountryChina
- Language:Chinese
-
Abstract:
Early identification and diagnosis of hepatocellular carcinoma (HCC) is necessary for improving survival rates of HCC patients. Studies have shown that the abnormal proteins released by tumor cells, i.e., the autoantibodies stimulated by tumor-associated antigens (TAAs), can be detected before a clinical diagnosis of HCC is made, and therefore, such proteins may become the new markers for the early diagnosis of HCC. This article reviews the application of several new autoantibodies to tumor-associated antigens in the diagnosis of HCC and points out that these autoantibodies have promising prospects and clinical significance in the early diagnosis of HCC.
